Tuesday, July 15, 2008

Recent Studies and Results




In recent years there have been many studies over this topic that has been published. The first whole genome linkage scan for intelligence was published in 2005 by Danielle Posthuma. Several more have been published since 2006 by several individuals. The first study done by Posthuma was a sample of 159 Dutch sibling pairs of genomes(152). The results from this test concluded that there were two significant linkages to general intelligence, one linkage on the long arm of the chromosome 2, the other linkage on the short arm of chromosome 6 (Posthuma 152). The linkage on chromosome 2 has also been linked to such mental disabilities as autism and dyslexia (Posthuma 152). Two more studies have been conducted to have similar findings. Confirming that chromosome 2 and 6 has particular influences on IQ score. A study conducted later by Luciano showed that word recognition was directly related to chromosome 2 (Posthuma and Geus 152). Other studies have confirmed to direct linkage to chromosome 14 as well. In further studies that where conducted by Hill, Chorney, Lubinshi, Thompson, and Plomin in 2002 found a more specific variant in a person’s intelligence. This was a chemical compound called Aldehyde Dehydrogenase 5 the gene that was found to increase the activity of this chemical was the ALDH5A1 gene found on chromosome 6 (Plomin). Increased levels of this chemical in the brain resulted in higher amounts of brain function and increased levels of IQ. There are various other genes that have been speculated to influence intelligence but have not been proven some of these genes are CTSD, PRNP, DRD2, CBS, BDNF and COMT (Postuma and Geus 153).

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